The Nowak lab is based in New York City at the Sandra and Edward Meyer Cancer Center of the Weill Cornell Medical College and NewYork-Presbyterian Hospital.
Dr. Nowak is also a member of the Department of Pharmacology and the Tri-Institutional PhD Program in Computational Biology and Medicine (CBM).
Prostate Cancer and Bladder Cancer
Our lab investigates the molecular and cellular mechanisms driving prostate and bladder cancer progression and metastasis. While primary tumors are often curable, metastatic disease remains the principal cause of cancer-related mortality. The mechanisms governing organ-specific metastasis in genitourinary cancers remain poorly understood, limiting our ability to develop effective therapeutic interventions.
Major Goals
We aim to define novel molecular targets that can prevent or eradicate metastases. Our ultimate goal is to translate these discoveries into therapeutic strategies that improve patient outcomes and survival.
Technologies
The Nowak lab integrates experimental and computational approaches to study cancer metastasis. Our toolkit includes somatically engineered mouse models (SEMMs), organoid systems, single-cell genomics, transcriptomics, metabolomics, bioinformatics and computational analysis, and signaling pathway analyses.