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Our lab is based in New York City at the Sandra and Edward Meyer Cancer Center of the Weill Cornell Medical College and NewYork-Presbyterian Hospital.
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Prostate Cancer and Bladder Cancer
Our lab investigates the molecular and cellular events driving prostate and bladder cancer progression and metastasis. The exact mechanisms that cause prostate and bladder cancer to metastasize to disparate tissues are not well understood, and have major implications for the successful therapy leading to significant decrease in the patients survival. The exact mechanisms that cause those genitourinary cancers to metastasize to different organs are not well understood, and a lack of comprehension has major implications for therapy.
Major Goals
The main goal of the lab is to define novel molecular targets that can prevent metastases and/or cure existing metastases. It is the hope that such targets will lead to therapeutic intervention, that is critical to strengthening the efficacy of patient care.
Technologies
The Nowak lab employs a wide range of technologies in its investigation of cancer metastasis, from genetically engineered mouse model systems and organoids to single-cell genomics, transcriptomics, metabolomics and signaling pathway analyses.